In children, the first signs of slapped cheek syndrome are usually mild cold-like symptoms including a slight fever, runny nose, sore throat, and headache. These initial symptoms appear around one to two weeks after infection. A few days later, the characteristic bright red rash appears on both cheeks, giving the condition its name. A lighter, lace-like rash may then develop on the body, arms, and legs, which can be slightly itchy. In adults, the rash may be less prominent or absent altogether, but joint pain and stiffness are common, particularly in the hands, wrists, knees, and ankles. This joint discomfort can last for several weeks or even months. Most people recover fully without complications. However, the NHS advises seeking medical advice if you are pregnant and have been in contact with someone who has slapped cheek, if your child has a blood disorder such as sickle cell disease, or if your immune system is weakened.